Improve Analytical Results with Metal-Free HPLC Components

Published on: 


Webinar Date/Time: Wed, Mar 8, 2023 11:00 AM EST

Dr. Jesse Bischof is presenting on how metal-ion contamination from stainless steel and other alloys can cause issues with separations of metal-active analytes. Dr. Bischof demonstrates the advantages of metal-free analysis, including eliminating the need for additives that mitigate metal surfaces and metal leaching.

Register Free:

Event Overview:

Trace corrosion of metal high-performance liquid chromatography (HPLC) components from common mobile-phase additives have a deleterious impact on separations and analytical results. Metals and materials like stainless steel, MP35N, Hastelloy, and titanium are chosen composition materials for mechanically strong columns, valves, needles, and more, but they are vulnerable to metal-ion contamination. This presentation will demonstrate:

  • How common additives, active compounds, and chelating agents lead to peak tailing, missing peaks, and silica poisoning
  • Various methods for preventing interaction between metal components and corrosive materials leading to contamination in the analyte flow path

Key Learning Objectives:

  • Viewers can expect to learn how to minimize poor analytical results by reducing the amount of metal in a flow path and how to eliminate the need for additives designed to mitigate metal surfaces and metal leaching.

Who Should Attend:

  • Researchers and product engineers who use chemical analysis tools or analytical additives.


Dr. Jesse Bischof
R&D Scientist
SilcoTek Corporation

Dr. Jesse Bischof began his career teaching high-school chemistry classes for two years before going to graduate school at Penn State where he earned his Ph.D. in chemistry. Upon completion of his degree in 2016, Jesse began his role as a researcher in SilcoTek's research and development department. Jesse’s expertise has helped customers in the medical and analytical markets to improve part performance, material characterization, and instrumentation. Currently, Jesse's research is focused on developing and optimizing bio-inert coatings as well as anti-fogging coatings.

Register Free: