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Novel Oligonucleotide Sample Clean-up and Method Optimizations It's Not “Just Analytical but With Bigger Columns”— Purification Insourcing and Technology Strategies How to Do More with Less: All Biopharmaceutical Batch Processes Can Benefit from Multi-Column Chromatography On Replication in Biopharmaceutical Analysis Tools for Investigating the Expanding Per- and Polyfluoroalkyl Substances Universe

Novel Oligonucleotide Sample Clean-up and Method OptimizationsIt's Not “Just Analytical but With Bigger Columns”— Purification Insourcing and Technology StrategiesHow to Do More with Less: All Biopharmaceutical Batch Processes Can Benefit from Multi-Column ChromatographyOn Replication in Biopharmaceutical AnalysisTools for Investigating the Expanding Per- and Polyfluoroalkyl Substances Universe

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View More Liquid Chromatography (LC/HPLC)Gas Chromatography (GC)Sample Preparation Mass Spectrometry Pharmaceutical Analysis Environmental Analysis Food and Beverage Analysis

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All App NotesBiological, Medical, and ClinicalBiopharmaceuticalsCannabisChiralEnvironmentalFood and BeverageGCGC-MSGeneralIndustrialLCLC-MSMedical/BiologicalMisc TechniquesPharmaceuticalsPolymersSample PrepSize-Exclusion Chromatography (SEC)Supercritical Fluid Chromatography (SFC)

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LCGC TV: Eliminating Matrix Effects: LC–MS Analysis of Biological Fluids

February 14, 2014

Frederic Lynen of Ghent University in Belgium discusses why LC–MS is the ideal analytical tool for the quantitative analysis of analytes in biological samples, and presents a new HILIC-based SPE approach to improve analyte recovery and sensitivity by removing phospholipids from samples.