Rapid, Sensitive LC–MS-MS Analysis of Nicotine and Metabolites

Rapid, Sensitive LC–MS-MS Analysis of Nicotine and Metabolites

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LCGC North America

A method is illustrated for the simultaneous analysis of nicotine, anabasine, and three of nicotine’s major metabolites (cotinine, nornicotine, and 3-hydroxycotinine) using the Kinetex 2.6 μm EVO C18 column.