SPME-GC-MS Analysis of Cigarette Smoke

December 15, 2008

A researcher from Shagrao Normal University (Shangrao, Jiangxi Province, China) used solid-phase microextraction (SPME) followed by gas chromatography?mass spectrometry (GC?MS) to analyze volatile organic compounds (VOCs) in cigarette smoke.

A researcher from Shagrao Normal University (Shangrao, Jiangxi Province, China) used solid-phase microextraction (SPME) followed by gas chromatography–mass spectrometry (GC–MS) to analyze volatile organic compounds (VOCs) in cigarette smoke. The researcher used a home-made smoking machine to produce the smoke. Various SPME fibers and desorption conditions were studied. The study found that the best fiber was coated with divinylbenzene–carboxen–polydimethylsiloxane and that a desorption temperature–time of 250 °C for 3 min was optimal. The method identified 70 VOCs and provided a precision of 2–11%.