|Articles|December 3, 2019

Strategies for Targeted and Untargeted Screening of Printing Ink Photoinitiators and Acrylates in Migration Studies Using UPLC and Quadrupole Time-of-Flight Mass Spectrometry

⦁ Benefits of utilizing a custom library in the targeted analysis of migration samples. ⦁ Insight into how proposed workflow is used in identifying targeted and untargeted photoinitiators in migration studies.


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Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.
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