Ahren Green | Authors

This article reviews historical bonding techniques still in use for manufacturing high performance liquid chromatography (HPLC) stationary phases today, and also examines some emerging technologies that may be able to tackle unmet needs in novel platforms and phase construction.

The traditional bonding techniques used to manufacture silica-particle-based HPLC stationary phases provide many benefits, but can emerging technologies tackle unmet needs? We assess current approaches and the potential for improvements.