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André Schreiber | Authors
Articles
Pesticide Residues Screening in Food Samples Using High Resolution and Accurate Mass LC–MS–MS
AB Sciex Application Note
Pesticide Residues Screening in Food Samples Using Hih resolution and Accurate Mass LC–MS–MS
AB SCIEX Application Note
LC–MS-MS-Based Strategies for the Targeted and Nontargeted Screening of Contaminants in Food, Environmental, and Forensic Samples
Liquid chromatography coupled to mass spectrometry (LC–MS) using electrospray ionization (ESI) is a powerful analytical tool for the analysis of a wide molecular weight range of polar, semivolatile, and thermally labile compounds.
Quantitation and Confirmation of the Pesticide Malathion in Fruit Samples using Multiple ReactionMonitoring and MS-MS-MS
LC–MS-MS instruments operating in Multiple Reaction Monitoring (MRM) are widely used for targeted quantitation on triple quadrupole and hybrid triple quadrupole linear ion trap (QTRAP® ) systems because of their well known selectivity and sensitivity. In MRM mode, the first quadrupole (Q1) filters a specific precursor ion; the collision cell (Q2) generates fragments (product ions) which are filtered in the third quadrupole (Q3). Although this double mass filtering greatly reduces noise there is always a chance that elevated background levels or matrix signals interfere with the targeted analyte.
The Use of Liquid Chromatography with Tandem Mass Spectrometry for the Analysis of Emerging Environmental Contaminants
Liquid chromatography with tandem mass spectrometry (LC–MS-MS) led to a revolution in environmental testing. The coupling of liquid chromatography with tandem mass spectrometry created a powerful analytical tool for the analysis of emerging environmental contaminants. Pharmaceuticals and personal care products, perfluorinated compounds, brominated flame retardants, and disinfection byproducts were chosen as examples to illustrate the use of this new technique in environmental analysis.