Anthony R. Kemperman | Authors


Stability of Formic Acid in Methanol Solutions and the Implications for Use in LC–MS Gradient Elution Analysis

Dilute formic acid solutions in methanol were found to decline in acid content with time, the extent of the decline depending upon the initial amount of water present in these solutions. The effect of the formic acid concentration change upon the separation of peptides using high performance liquid chromatography (HPLC) is examined briefly.