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SIFT-MS: Real-Time Volatiles Analysis for Continuous Manufacturing of Pharmaceuticals Automated Sample Prep in Regulated and Nonregulated Labs Just Got Easier Trends in Modern LC Separation Workflows Strategies for Improving Peak Tailing The Evolution of Breath Analysis

SIFT-MS: Real-Time Volatiles Analysis for Continuous Manufacturing of PharmaceuticalsAutomated Sample Prep in Regulated and Nonregulated Labs Just Got EasierTrends in Modern LC Separation WorkflowsStrategies for Improving Peak TailingThe Evolution of Breath Analysis

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View More Liquid Chromatography (LC/HPLC)Gas Chromatography (GC)Sample Preparation Mass Spectrometry Pharmaceutical Analysis Environmental Analysis Food and Beverage Analysis

Liquid Chromatography (LC/HPLC)Gas Chromatography (GC)Sample PreparationMass SpectrometryPharmaceutical AnalysisEnvironmental AnalysisFood and Beverage Analysis

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All App NotesBiological, Medical, and ClinicalBiopharmaceuticalsCannabisChiralEnvironmentalFood and BeverageGCGC-MSGeneralIndustrialLCLC-MSMedical/BiologicalMisc TechniquesPharmaceuticalsPolymersSample PrepSize-Exclusion Chromatography (SEC)Supercritical Fluid Chromatography (SFC)

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Björn Mautz | Authors

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Monitoring of On-column Methionine Oxidation as Part of a System Suitability Test During UHPLC–MS/MS Peptide Mapping

Long-term column use can lead to on-column methionine oxidation during LC–MS/MS peptide mapping of antibody-based biotherapeutics. Following the approach described here minimizes the risk of measuring oxidative artifacts, and helps generate high quality data to provide reliable quantitative information about product-related heterogeneities.