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Food and Beverage Analysis
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GC–MS
Gas Chromatography (GC)
HILIC
HPLC
Ion Chromatography
LCGC Interviews
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LCGC TV: Sample Preparation
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Liquid Chromatography (LC/HPLC)
Market Profiles
Mass Spectrometry
Medical/Biological
Multidimensional GC
Multidimensional LC
Peer-Reviewed Articles
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Preparative-Scale Chromatography
Process Analytical Technology (PAT)
Quality Control/Quality Assurance (QA/QC)
Quality by Design (QbD)
Regulatory Standards, GLP and GMP Compliance
Sample Preparation
Size-Exclusion Chromatography (SEC)
Solid-Phase Extraction (SPE)
Supercritical Fluid Chromatography (SFC)
Supercritical Fluid Extraction (SFC)
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Cynthia Quan

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Articles

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HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies

Taylor Yonghua Zhang;Cynthia Quan;Michael W. Dong
November 1st 2014

This instalment describes recent advances and best practices in HPLC analysis of intact monoclonal antibodies (mAbs) and their variants and fragments.

HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies

HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies

Taylor Yonghua Zhang;Cynthia Quan;Michael W. Dong
October 1st 2014

The latest approaches to antibody characterization go beyond ion-exchange, size-exclusion, and reversed-phase modes to make use of affinity, hydrophobic interaction, mixed-mode, and HILIC techniques.

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