Florian Füssl received his Dr. rer. nat. degree from the University of Salzburg, Austria. Since 2016 he has been a postdoctoral researcher in the Characterization and Comparability Laboratory of Jonathan Bones at NIBRT in Dublin, Ireland. His main focus is the development of novel methods for the characterization of complex biopharmaceuticals using liquid chromatography–mass spectrometry (LC–MS) techniques with special emphasis on intact native protein analysis.
This article explores the potential of microchip capillary electrophoresis–mass spectrometry (CE–MS) for the characterization of intact biopharmaceuticals, and how this technique can effectively be employed to monitor essential quality attributes of interest.