Grace

The quality and consistency of lipid nanoparticles (LNPs) depend on the purity of their component lipids—a challenge that demands robust purification strategies. Using high-purity silica chromatography resins help enable consistent, scalable purification of those component lipids. Read the article to uncover three major challenges in the purification process, and the variety of ways high quality silica resins can help overcome the challenges of chromatographic process development and scale-up for lipid purification.

Not all chromatography resins are created equal. Off-the shelf chromatography resins might not always meet the rigorous purification requirements of biopharmaceutical manufacturing. Custom bonded silica can address a wide range of separation challenges, leading to real performance improvements. Discover more about the latest innovations in chromatography silica.

Enzymes in their free form can present challenges, but immobilizing enzymes on solid silica supports can significantly improve enzyme stability, recovery, and reusability. Silica’s mechanical strength and chemical robustness enable consistent performance, easier purification, and cost‑effective reuse. Read the article to learn more about the advantages of solid silica supports for enzyme immobilization.

Particularly in the pharmaceutical industry, drug purity isn’t just a goal – it’s essential for achieving safety, stability and efficacy. However, purification is easier said than done, especially with challenging molecules like DNA and RNA “oligonucleotides,” due in large part to their diversity and the range of impurities that can be generated during production. Before you choose a chromatography resin for your next purification application, consider these five characteristics. Download the article to learn more.

Not all chromatography resins are created equal. Off-the-shelf chromatography resins might not always meet the rigorous purification requirements of biopharmaceutical manufacturing. Custom bonded silica from Grace can address a wide range of separation challenges, leading to real performance improvements. Discover more about the latest innovations in chromatography silica from Grace, including VYDAC® and DAVISIL®.

Particularly in the pharmaceutical industry, drug purity isn’t just a goal – it’s essential for achieving safety, stability and efficacy. However, purification is easier said than done, especially with challenging molecules like DNA and RNA “oligonucleotides,” due in large part to their diversity and the range of impurities that can be generated during production. Enter DAVISIL® chromatographic silica, with a wide range of pore diameters and particle sizes to meet your specific application, performance and sustainability requirements. Before you choose the chromatography resin for your next purification application, take a look at these 5 considerations.