Julia Khandurina | Authors

In this article the authors report on a combinatorial natural product discovery methodology that uses a viral vector system to transfer secondary metabolite-related enzymes from C. roseus to tobacco cell cultures. Using high-resolution separation techniques, including HPLC, CE and MS, they describe the analysis of secondary metabolite patterns.

The authors used HPLC and CE to monitor changes in combinatorial genetics mediated secondary metabolite generation.