Analysis of Combinatorial Natural Products by HPLC and CE

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LCGC Europe

LCGC Europe, LCGC Europe-02-01-2004, Volume 17, Issue 2
Pages: 104–111

In this article the authors report on a combinatorial natural product discovery methodology that uses a viral vector system to transfer secondary metabolite-related enzymes from C. roseus to tobacco cell cultures. Using high-resolution separation techniques, including HPLC, CE and MS, they describe the analysis of secondary metabolite patterns.