Kenneth Berthelette | Authors

Kenneth Berthelette works as a senior scientist in the Consumables and Lab Automation Group of Waters Corporation where he focuses on marketing support and collateral generation. Ken’s areas of expertise include reversed‑phase LC method development and troubleshooting and HILIC method development.


Modifying the Metal Surfaces in HPLC Systems and Columns to Prevent Analyte Adsorption and Other Deleterious Effects

A novel surface modification technology has been developed to reduce interactions between analytes and metal surfaces in HPLC instruments and columns. We demonstrate the impact of this technology on peak symmetry, peak area, and injection-to-injection and column-to-column reproducibility for several metal-sensitive analytes.