Lakshmi Subbarao | Authors

Superficially porous particles (SPPs) are routinely used in analytical liquid chromatography (LC) columns, but they also provide benefits for preparative LC columns for use in pharmaceutical discovery laboratories and high-throughput environments. In this study, a preparative method using SPP-packed column had a 45% decrease in run time over a method using columns packed with fully porous particles, at standard flow.

According to the FDA policy statement, developing stereoisomeric drugs, each enantiomer should be evaluated.

In the past decade, supercritical fluid chromatography (SFC) has been established as a cost-effective, sustainable, and green purification technology for pharmaceutical and related industries.