Lakshmi Subbarao | Authors


Developing a Fast Purification Method for a Natural Product with a Preparative LC Column Packed with Superficially Porous Particles

Superficially porous particles (SPPs) are routinely used in analytical liquid chromatography (LC) columns, but they also provide benefits for preparative LC columns for use in pharmaceutical discovery laboratories and high-throughput environments. In this study, a preparative method using SPP-packed column had a 45% decrease in run time over a method using columns packed with fully porous particles, at standard flow.