Leandro Wang Hantao | Authors

Articles

Solid-Phase Microextraction Combined with Flow-Modulated Comprehensive Two-Dimensional GC for Screening Leachables in the Pharmaceutical Industry

A simple method for the analysis of leachables using solid-phase microextraction (SPME) and comprehensive two-dimensional gas chromatography, coupled to mass spectrometry (GCxGC–MS). This fully automated method bypasses the use of solvents and excessive sample handling. Four potential leachables were tentatively identified.

Solid-Phase Microextraction Combined with Flow-Modulated Comprehensive Two-Dimensional Gas Chromatography for Screening Leachables in the Pharmaceutical Industry

Nanomaterials are extremely useful as sorbents for sample preparation, because of their varied morphologies, high surface area, surface-tovolume ratio, porosity, and ability to interact with samples in a variety of ways. Here, we review how nanomaterials are being used in a variety of sample preparation techniques, such as dispersive solid-phase extraction (dSPE), solid-phase microextraction, stir-bar sorptive extraction, and matrix solid-phase dispersion.