Mani Iyer | Authors


Molecular Weight Analysis of Glatiramer Acetate and Related Compounds by Size-Exclusion Chromatography with Multi-Angle Light Scattering Detection (SEC-MALS)

A method was developed for the molecular weight characterization of heterogeneous polymer mixtures, such as heparins and glatiramer acetate, noting that single molecular structures are not adequate for creating a molecular weight calibration curve. That limitation is overcome in this work, which demonstrates method validation and application to process samples.