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© 2022 MJH Life Sciences™ and Chromatography Online. All rights reserved.
PRA International, Early Development Services, Bioanalytical Laboratory, Assen, The Netherlands
The technical requirements for a successful LC–MS/MS method for the quantitation of biopharmaceuticals are presented and the advantages and disadvantages compared to ligand-binding assays are evaluated.
Advances in Liquid Chromatography–Tandem Mass Spectrometry (LC–MS–MS)-Based Quantitation of Biopharmaceuticals in Biological Samples