Polar neurotransmitters are difficult to retain using ODS columns. In this work we show two different methods to retain these polar analytes on the multi-mode Scherzo SS-C18 column. The versatility in retention characteristics with simple changes in mobile phase is highlighted.
The challenging retention of polar organic acids in reversed phase conditions is accomplished using a unique multi-mode stationary phase.
The Intrada Amino Acid column has been shown to be a viable solution for the analysis of amino acids by LC–MS without derivatization.