Teledyne Tekmar

Purification of peptide-peptoid hybrids can be obtained by reversed-phase chromatography with excellent recovery and resolution.

The ability to collect compounds is related to the ability to detect them. Many possess weak or non-existent chromophores, causing UV detection to exhibit poor yields. 

Purification of peptide-peptoid hybrids can be obtained by reversed phase chromatography with excellent recovery and resolution.

The ability to collect compounds is directly related to the ability to detect them. Many compounds possess weak or non-existent chromophores which causes UV detection to exhibit poor yields.

This project will evaluate the performance and versatility of the AutoMate-Q40 for the extraction of Imidazolinone herbicides.

Teledyne Tekmar

The United States Environmental Protection Agency (US EPA) has established the Unregulated Contaminant Monitoring Program to collect data for contaminants suspected to be present in drinking water (1). The US EPA is currently proposing Unregulated Contaminant Monitoring Rule 3 (UCMR 3) which will collect data from January 2013 through December 2015. Because of the impact on public health and safety, it is vital to have a system that can detect and analyze for these compounds at low levels.

With advances in instrumentation and without regulatory method constraints, 1,4-dioxane can be detected at the part-per-billion (ppb) level, despite its poor purge efficiency. This application will manipulate purge and trap, as well as GC–MS parameters, to create a more efficient method to reduce cycle times. This study will utilize a Teledyne Tekmar Atomx Automated Sample Prep System in conjunction with an Agilent 7890/5975 GC–MS. A linear calibration and method detection limits (MDLs) for 1,4-dioxane will be established using this method.

The United States Food and Drug Administration (U.S. FDA) and the European Union (EU) have published regulations and provided guidance on the use of chemicals in food packaging materials. Tekmar provides method parameters for the HT3â„¢ Automated Headspace Analyzer for the determination of VOCs that may be contained in food contact packaging materials under various conditions. Temperature and mixing parameters were investigated to determine which VOCs may be released when subjected to these conditions.

EPA Method 8260 is used to determine volatile organic compounds (VOC's) in a variety of matrices including ground and surface waters. This method is commonly used in environmental laboratories where gas chromatography (GC), mass spectrometry (MS) and purge and trap (P&T) technology are used for the analysis and subsequent detection of VOC's.

Purge and trap concentration (P&T) along with gas chromatographic analysis is a widely used method for the detection of volatile organic compounds (VOCs). This methodology was developed to achieve the high sensitivity necessary to determine VOCs in drinking water according to EPA Method 524.2. Research is now complete and the EPA currently proposes a revision to this method that may include a revised list of analytes including iodinated trihalomethanes, fuel oxygenates, and Contaminant Candidate List 3. This new method will be 524.3 and may include new parameter optimizations not previously permitted in 524.2 as well as the ability to use selective ion monitoring (SIM) analysis for troublesome compounds.