Tina Fanning | Authors


Extraction of Loperamide and N-Desmethyl Loperamide from Blood Followed by LC–MS/MS Analysis

This application note outlines a simple three-step method for the extraction of loperamide and its main metabolite, N-desmethyl loperamide, from blood. UCT’s Clean Screen® XCEL I column provides users with the same level of sample clean-up as traditional SPE while allowing the elimination of timely conditioning and wash steps.

In-Well Hydrolysis Using UCT’s Refine™ Ultra-Filtration Technology

UCT’s Refine™ Ultra-Filtration Technology allows for sample precipitation and filtration to occur simultaneously in the individual column or well. A novel, hydrophobically treated, submicrometer frit combination facilitates the removal of sample proteins without a complicated extraction.