Yun Lou | Authors

South San Francisco

California

Yun Lou is a research associate at Genentech, Inc., Protein Analytical Chemistry

Articles

Size-Exclusion Chromatography for the Analysis of Complex and Novel Biotherapeutic Products

This study presents applications of size-exclusion chromatography (SEC) for characterization and quality control of novel biotherapeutic products, including antibody–drug conjugates, hydrophobic proteins, and coformulations. Examples of modifying SEC mobile-phase composition and running conditions to modulate the separation are discussed, as well as approaches and strategies for analyzing atypical protein products such as coformulations.