The Column-03-10-2014

Market Profile: Flow Cytometers

Kate Mosford of The Column about the importance of solid-phase microextraction (SPME) in food analysis.

A column classification system for SFC to help with method development has been developed. This article demonstrates how the system can be used to select a column when developing a new SFC method.

Certain considerations must be made with regards to the overall ?ow path used in a SFC analysis to ensure additional obstacles are not introduced inadvertently. This article provides more information.

Scientists in Malaysia have developed a useful metabolomics approach that could aid analysts working in natural drug discovery. The team applied liquid chromatography–mass spectrometry (LC–MS) coupled with principle component analysis (PCA) to screen more than 4000 natural extracts for novel photosensitizer drugs.

Click the title above to open The Column March 10, 2014 North American issue, Volume 10, Number 4, in an interactive PDF format.

Click the title above to open The Column March 10, 2014 Europe & Asia issue, Volume 10, Number 4, in an interactive PDF format.

LC–MS Deconstructs the "Poppy Seed Defense"

The efficiency of protein separation by ion-exchange chromatography could be increased by up to a factor of 5 according to a new study, potentially speeding up biopharmaceutical production.1 Christy Landes of Rice University in Texas (USA) and her team performed the first molecular-scale investigation into protein ion-exchange chromatography by using direct super-resolution techniques and the stochastic theory.