Hyphenated approaches to analysis have received much attention over the last three decades to the extent that techniques such as GC?MS, GC?FTIR and LC?MS have ? in the relevant fields ? become indispensable parts of the analyst?s arsenal. This concept has been extended to include multi-hyphenated techniques, where the chromatography is preceded by analyte extraction from a sample matrix. In the field of GC?MS, examples include thermal, sorptive or headspace extraction, with subsequent preconcentration, for instance, by thermal desorption (TD).