The Column-04-11-2017

The Column

Volatile Separation: A Low-Density Approach

April 11, 2017

Cover Story

13

5

Separating and quantifying both volatile and nonvolatile compounds in complex mixtures is a costly and time-consuming process presenting significant technical challenges. Fabrice Gritti from the Instrument, Core Research, Fundamental Group at Waters Corporation discusses his team’s unique solution to this problem, combining high-vacuum technology and low-density fluid chromatography (LDFC) with carbon dioxide as a mobile phase for a rapid and complete baseline separation of both volatile and nonvolatile compounds on a single instrument, single column, and a single run without the associated loss of resolution.

Exploring Ocular Disease Using Metabolomics

April 11, 2017

News

13

5

Researchers from the Medical University of Bialystok, Poland, have used metabolomics and liquid chromatography quadrupole time‑of‑flight mass spectrometry (LC–QTOF‑MS) to study human ocular fluids.

Waters Announce Malaysian Expansion

April 11, 2017

News

13

5

Waters Corporation has announced the opening of a new Solution Centre in Petaling Jaya, Selangor, Malaysia. The new facility is designed to advance liquid chromatography and mass spectrometry analytical capabilities, developing new applications and offering training to scientists within its demonstration and training facilities.

Identifying Fraudulent Saffron Using UHPLC–HRMS/MS and Metabolomics

April 11, 2017

News

13

5

Researchers from the University of Chemistry and Technology in Prague, Czech Republic, have developed a saffron authentication process based on ultrahigh-performance liquid chromatography coupled to high resolution tandem mass spectrometry (UHPLC–HRMS/MS) and multivariate data analysis.

Shimadzu Launches European Innovation Center

April 11, 2017

News

13

5

Shimadzu Corporation has opened a new European Innovation Center in Duisburg, Germany. The new facility will merge Shimadzu’s state-of-the-art analytical technologies with prominent topics, market expertise, and scientific research guided by some key opinion leaders.

Reach Separations Celebrate 5th Birthday

April 11, 2017

News

13

5

Reach Separations is celebrating its 5th anniversary with a record year of growth.

Tips & Tricks GPC/SEC: Protein Analysis with Size-Exclusion Chromatography

April 11, 2017

Features

13

5

Gel permeation chromatography/size-exclusion chromatography (GPC/SEC) is the standard method to separate samples by molecular size. In protein analysis, size-exclusion chromatography is either applied to detect and quantify aggregation, or to measure the complete molar mass distribution. However, method development is not trivial and the choice of suitable detection options is crucial.

Targeting Specific Matrix Interferences for Sample Preparation

April 11, 2017

Features

13

5

This article describes the evolution of traditional solid-phase extraction (SPE) into new techniques that are customized to the characteristics of specific matrices, including the removal of β-glucuronidase from urine samples and the removal of phospholipids and proteins from plasma samples.

Vol 13 No 5 The Column April 11, 2017 Europe and Asia PDF

April 11, 2017

Issue PDF

13

5

Click the title above to open The Column April 11, 2017 Europe & Asia issue, Volume 13, Number 5, in an interactive PDF format.

Vol 13 No 5 The Column April 11, 2017 North American PDF

April 11, 2017

Issue PDF

13

5

Click the title above to open The Column April 11, 2017 North American issue, Volume 13, Number 5, in an interactive PDF format.

Ellutia Chromatography Solutions Open New Facility

April 10, 2017

News

13

5

Ellutia Chromatography Solutions has opened a new state‑of‑the-art facility in Ely, Cambridgeshire, UK, consolidating Ellutia’s offices, laboratories, production, and warehouse on one 15,000 sq. ft. site.