The Column-06-19-2014

A simple, rapid, and robust UHPLC method for the simultaneous determination of polyphenols, methylxanthines, sweeteners, and flavouring substances as well as some common preservatives has been developed using an automated method scouting and method optimization workflow.

Incognito presents his pick of the review articles that have helped him progress in his chromatography career.

The 8th Annual International Conference on Packed Column SFC (SFC 2014) will take place at the Congress Center Basel in Switzerland from 8–10 October 2014.

The Column
Cover Story

June 19, 2014

James Frahill, who is a Research Analyst at the Pfizer Process Development Centre (Cork, Republic of Ireland), spoke to Bethany Degg of The Column about the role of the chromatographer in the pharmaceutical process development group at Pfizer.

This article describes the advantages of miniaturizing laboratory instruments, as well as the challenges to adapt to and overcome

The Column

Profiling impurities in MDMA (also known as ecstasy) is essential to forensic science as different profiles can provide clues about the source. Two researchers from Michigan State University (Michigan, USA) investigated the effect of liquid–liquid extraction (LLE), headspace solid-phase microextraction (HS–SPME), and different gas chromatography temperature programmes highlighting the need for standardized procedures.

The Column

June 19, 2014

Dried blood spot (DBS) sampling and high performance liquid chromatography coupled to high-resolution tandem mass spectrometry (HPLC–MS) has been demonstrated in the routine testing of athletes for anabolic steroid esters.

The Column

A new method for the purification of adenovirus serotype 5 (Ad5) by two-column, size-exclusion simulated countercurrent chromatography (SEC) has been published in the Journal of Chromatography A.

Researchers at the Universite de Montreal in Canada have developed and validated a new liquid chromatography tandem mass spectrometry (LC–MS–MS) method to identify compounds present in suspected counterfeit or even adulterated erectile dysfunction drugs. According to the study published in the Journal of Chromatography A, the method has now been introduced to the Inspectorate Laboratory Programme at Health Canada (Canada).

Click the title above to open The Column June 19, 2014 North American issue, Volume 10, Number 11, in an interactive PDF format.

Click the title above to open The Column June 19, 2014 Europe & Asia issue, Volume 10, Number 11, in an interactive PDF format.