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The Column-06-19-2014
The Column
Ultra-Fast Analysis of Alkaloids and Permitted Additives in Dark Chocolate Products
June 19, 2014
Features
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A simple, rapid, and robust UHPLC method for the simultaneous determination of polyphenols, methylxanthines, sweeteners, and flavouring substances as well as some common preservatives has been developed using an automated method scouting and method optimization workflow.
Incognito: Zero to Hero... The Power of the Review Article
June 19, 2014
Features
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Incognito presents his pick of the review articles that have helped him progress in his chromatography career.
International Conference on Packed Column SFC (SFC 2014)
June 19, 2014
Features
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The 8th Annual International Conference on Packed Column SFC (SFC 2014) will take place at the Congress Center Basel in Switzerland from 8–10 October 2014.
Teaching Old Drugs New Tricks
June 19, 2014
Cover Story
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James Frahill, who is a Research Analyst at the Pfizer Process Development Centre (Cork, Republic of Ireland), spoke to Bethany Degg of The Column about the role of the chromatographer in the pharmaceutical process development group at Pfizer.
Thinking Small: The Benefits and Challenges of Miniaturization
June 19, 2014
Features
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This article describes the advantages of miniaturizing laboratory instruments, as well as the challenges to adapt to and overcome
Profiling MDMA Impurities Using HS–SPME
June 19, 2014
News
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Profiling impurities in MDMA (also known as ecstasy) is essential to forensic science as different profiles can provide clues about the source. Two researchers from Michigan State University (Michigan, USA) investigated the effect of liquid–liquid extraction (LLE), headspace solid-phase microextraction (HS–SPME), and different gas chromatography temperature programmes highlighting the need for standardized procedures.
DBS in Doping
June 19, 2014
News
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Dried blood spot (DBS) sampling and high performance liquid chromatography coupled to high-resolution tandem mass spectrometry (HPLC–MS) has been demonstrated in the routine testing of athletes for anabolic steroid esters.
Optimizing Viral Vector Purification
June 19, 2014
News
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A new method for the purification of adenovirus serotype 5 (Ad5) by two-column, size-exclusion simulated countercurrent chromatography (SEC) has been published in the Journal of Chromatography A.
New LC–MS–MS Method to Detect Counterfeit Drugs
June 19, 2014
News
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Researchers at the Universite de Montreal in Canada have developed and validated a new liquid chromatography tandem mass spectrometry (LC–MS–MS) method to identify compounds present in suspected counterfeit or even adulterated erectile dysfunction drugs. According to the study published in the Journal of Chromatography A, the method has now been introduced to the Inspectorate Laboratory Programme at Health Canada (Canada).
Vol 10 No 11 The Column June 19, 2014 North American PDF
June 19, 2014
Issue PDF
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Click the title above to open The Column June 19, 2014 North American issue, Volume 10, Number 11, in an interactive PDF format.
Vol 10 No 11 The Column June 19, 2014 Europe and Asia PDF
June 19, 2014
Issue PDF
10
11
Click the title above to open The Column June 19, 2014 Europe & Asia issue, Volume 10, Number 11, in an interactive PDF format.