The Column-10-05-2014

Click the title above to open The Column October 05, 2014 Europe & Asia issue, Volume 10, Number 18, in an interactive PDF format.

The development of a column-switching technique based on on-line preconcentration and HRAM–MS to obtain fast and accurate results for the determination of algal toxins in drinking water is discussed.

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Researchers from the Institute of Food Chemistry at Westfälische Wilhelms‑Universität Münster in Germany have developed an optimized high performance liquid chromatography coupled with mass spectrometry (HPLC–MS–MS) method using multiple reaction mode (MRM) and MRM3 for detecting horse and pork in highly processed food.

Scientists from CEITEC Masaryk University are collaborating with clinicians from the Department of Respiratory Diseases and TB at the University Hospital Brno (Brno, Czech Republic) to improve the diagnosis of cystic fibrosis, specifically in newborn babies. In a new study published in the Journal of Chromatography A, a new "skin wipe" sweat sampling method is presented that reduces the time required for sampling to under a minute and utilizes capillary electrophoresis (CE) to simultaneously determine chloride, sodium, and potassium ions in sweat samples.

Liquid chromatography coupled to triple quadrupole tandem mass spectrometry (LC–MS–MS) in multiple reaction monitoring (MRM) mode is widely considered as the gold standard for pesticide analysis. In this article recent developments in LC–MS–MS technology to meet increasing regulatory demands and productivity targets in quality control and contract laboratories are explored.

In the second of a two-part Q&A, The Column spoke to Paul A. Sutton, a research fellow in the Petroleum and Environmental Geochemistry Group at Plymouth University (Plymouth, UK), about his experience with high temperature gas chromatography (HTGC), and his best practices for analysts in the lab.

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This article provides some tips and tricks for monitoring sample recovery and peak area using GPC/SEC.

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Features

October 06, 2014

To understand how the HPLC system works, it can be useful to first identify the basic components of virtually every system. Armed with that information, envisioning the HPLC system as comprised of three different zones - each with unique characteristics and each with its own set of requirements - can offer further guidance.

Click the title above to open The Column October 05, 2014 North American issue, Volume 10, Number 18, in an interactive PDF format.