LCGC Asia Pacific-09-01-2007
LCGC Asia Pacific
Routine Switching between High and Low pH on Xbridge HPLC Columns
September 01, 2007
Application Notes
10
3
The effect of switching between high and low pH mobile phases on a single analytical HPLC column was investigated. The ability to rapidly switch between pH extremes on XBridge columns without special washing/re-equilibration steps dramatically reduces the time for separation of pharmaceutical compounds.
Solvent Conservation
September 01, 2007
LC Troubleshooting
10
3
How can you reduce mobile phase expenses?
A Novel Method for the High-Speed Determination of Fuel Diluents in Lubricating Oils
September 01, 2007
Application Notes
10
3
The performance of lubricating oil is significantly degraded by the presence of fuel contaminants such as gasoline and diesel. Recycled oil is particularly susceptible to this form of contamination. Consequently, producers and distributors of lubricating oil must go to great lengths to ensure the levels of fuel contamination are kept to a safe limit (typically 4–5%) in these products.
Living in interesting times
September 01, 2007
China Focus
10
3
This feature highlights some of the current analytical research being undertaken across China by focusing on the work of several research groups at academic institutions.
Rapid Compound Identification from Crude Oil Enabled by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
September 01, 2007
Application Notes
10
3
The analysis of crude oil by means of different atmospheric pressure ionization (API) techniques is described. Crude oil is analysed without any separation prior to API-Fourier transform mass spectrometry. The use of a quadrupole/hexapole device to selectively enhance a certain mass range is demonstrated. Automated generation of molecular formulas from accurate mass measurements enables rapid compound identification.
On-Line and Off-Line Application of Micro-SPE (MEPS)
September 01, 2007
Application Notes
10
3
Solid-phase extraction (SPE) has revolutionized sample preparation. Variations on the technique offer enhanced recovery, greater speciation and reduced solvent and sample consumption over other techniques. Micro-extraction packed sorbent (MEPS) is the miniaturization of conventional SPE from millilitre to microlitre bed volumes that allows SPE to be used with very small samples. The manipulation of the small volumes is achieved with a precision gas tight syringe. With a typical void volume of 7 μL, the volume of solvent eluted from MEPS is compatible with GC and LC inlets making it ideal for integration into an automated sampling system for on-line SPE.
A Miniaturized Method to Determine Epoxidized Soybean Oil in Baby Food
September 01, 2007
Miniaturized Method
10
3
This article describes the development of a routine method to analyse epoxidized soybean oil (ESBO) in baby food...
Advanced Topics in Solid-Phase Extraction: Chemistries
September 01, 2007
Sample Preparation Perspectives
10
3
In this instalment of "Sample Preparation Perspectives", columnist Ron Majors discusses advanced topics such as multimodal SPE, restricted-access media, molecular imprinted polymers, immunoaffinity extraction phases and other class-or compound-specific sorbents...