LCGC Asia Pacific-09-01-2019

LCGC Asia Pacific

LCGC Asia Pacific August/September 2019 Regular Issue PDF

September 01, 2019

Issue PDF

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Click the title above to open the LCGC Asia Pacific August/September 2019 regular issue, Vol 22, No 3, in an interactive PDF format.

Strategies for the Quantification of Endogenously Present Small Molecules in Biological Samples

July 01, 2019

Pharmaceutical Perspectives

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The main objective of this review article is to provide a clear summary of the different methods that can be used to quantify endogenous small molecules. Because of the increased use of mass spectrometry (MS) in the field of bioanalysis, a special focus will be placed on quantification by liquid chromatography (LC)–MS. Practical recommendations to face this bioanalytical challenge, in particular in terms of method validation, will also be provided.

GC×GC–TOF-MS and Comprehensive Fingerprinting of Volatiles in Food: Capturing the Signature of Quality

May 01, 2019

Features

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Chemical fingerprinting can provide evidence for quality differences resulting from botanical and geographical origins of primary food ingredients, post-harvest practices, production processes (such as traditional versus industrial processes), and the shelf-life evolution of finished products. This article discusses the strategic role and potential of comprehensive two-dimensional gas chromatography (GC×GC) combined with time-of-flight mass spectrometry (TOF-MS) and pattern recognition using template matching for data processing to unravel the quality traits of high-quality food products. Practical examples dealing with high-quality cocoa and extra-virgin olive oil are described.