Dwight R. Stoll | Authors


Where Has My Efficiency Gone? Impacts of Extracolumn Peak Broadening on Performance, Part I: Basic Concepts

Dispersion of analyte zones outside of the column often compromises the quality of an LC separation—particularly in smaller columns with smaller particles. We explain basic concepts in extra-column dispersion from the point of view of an entire instrument.

Columns - Tips for Liquid Chromatography Coupled with Charged Aerosol Detection

Charged aerosol detection (CAD) is a powerful complement to ultraviolet (UV) absorbance and mass spectrometric (MS) detection for liquid chromatography (LC), particularly for analytes that have no UV chromophore, or do not ionize well by electrospray ionization. This article explores how to successfully use this technique.