LCGC North America-02-01-2004

From the Editor

Products

Peaks of Interest

This column discusses potential sources and ways to avoid out-of-specification (OOS) results and highlights the draft FDA guidelines on OOS investigations.

"A well-prepared sample, a well-defined analytical goal, the appropriate use of accurate mass, reproducible retention times, and good instrument control generate unassailable data..."

Which curve-fitting function should be used?

This article establishes the estimation of the uncertainty associated with the chromatographic determination of biogenic amines.

This review discusses the operating principles of and current applications for two-dimensional gas chromatography with heartcutting.

Calendar of Events

New miniaturized liquid-membrane extraction designs are especially suited for speciation studies of metal ions in small amounts of biological fluids.

The authors evaluted the performance of a high-capacity anion-exchange column specifically designed for use with hydroxide eluents for fulfilling the requirements of EPA Method 300.0 Part A and compared the results with data generated with an anion-exchange column using carbonate eluents.