LCGC North America-08-01-2006

In Part I of this two-part look at spectral interpretation, Michael Balogh examined the ability to see and appreciate the product of our analytical devices. In Part II, he takes a closer look at the tools of the trade.

Carryover is the appearance of an analyte in a run when a clank containing no analyte is injected. In this month's "LC Troubleshooting," John Dolan shows us how to measure it, and some ways to reduce carryover.

News from the chromatography industry.

After having collected some industry accepted practices for implementing new LC technology, the duo discuss FDA guidance available on the subject with respect to LC, and using some recently introduced LC technology.

In this installment of "Column Watch," Ron Majors traces the developments in modern column design in analytical and preparative configurations and speculates on future directions.

The authors work to develop a universal high performance liquid chromatography method that is capable of simultaneously retaining and separating both cations and anions within a single chromatographic analysis for the purpose of quantification in pharmaceutical products.

Analytical technologies have been applied to many problems of the modern world, though usually in the domain of the laboratory or to regulate production on the factory floor. However, modern instrumentation can provide valuable information in many other settings as well. Security applications demand sensitive information, accurate information and fast information. These are precisely the kinds of problems that instrumentation has been solving in the research setting for decades. The application of analytical technology to the security of nations, facilities, and people has become an important segment of the industry.