Ira S. Krull | Authors


A Review of Recent Developments in Analytical Characterization of Glycosylation in Therapeutic Proteins

Advanced separation and mass spectrometry methods enable comprehensive profiling of the inherent glycan heterogeneities of protein therapeutics. In particular, reversed-phase HPLC–based multiattribute methods (MAMs) provide a wealth of information, and other techniques, such as HILIC and CE-MS, also continue to evolve.