A Comprehensive Workflow for PFAS Analysis in Wastewater with Extended EPA Draft Method 1633 List

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This study assesses a workflow developed for PFAS analysis in wastewater, based on the existing EPA draft Method 1633 with additional PFAS of varying size and functional group. This workflow contains off-line solid phase extraction (SPE) and a clean-up step, followed by LC-MS/MS analysis, and automatic reporting using SLIMS. The workflow demonstrates a reliable solution for the targeted analysis of PFAS in complex matrices with high robustness.