Analysis of N-Nitrosodimethylamine (NDMA) Impurity in Rantidine Products Using SIFT-MS
Quantitative analysis of volatile nitrosamine impurities in drug products is greatly simplified using SIFT-MS and has a three-fold throughput advantage (excluding sample prep benefits) over chromatographic methods. This application note describes the headspace-SIFT-MS analysis of ranitidine products which achieves a limit of quantitation of 2 ng g-1 for NDMA in 500 mg of drug product.
Application of LC-UV/MS Workflows to Increase Efficiency in Impurity Profiling of GLP-1 Analogs
June 18th 2025In this study, the unique capabilities of a LC-UV/MS workflow to accelerate analysis are demonstrated in the identification of impurities related to GLP-1 analogs that underwent chemical and thermal stress conditions.
Accelerating Method Development and Manufacturing of GLP-1 Analogs with LCUV-MS
June 18th 2025In this study, we present a QC-friendly LC-UV/MS workflow designed to alleviate the workload on analytical laboratories. Access to orthogonal mass data allows supporting labs to make quicker and more informed decisions during method development, reducing errors, and increasing overall productivity.
