Different classes of antibodies, including IgG1, 2 and 4, are immediately reduced down to light and heavy chain without the need of enzymes, denaturing or reducing agents using inline EC-LCMS. The workflow can be used for IdeS digested mAbs and does not affect the quantitation of acid labile species such as sialylated N-glycans.
Inside the Laboratory –– Women in Separation Science Edition
April 25th 2024Inside the Laboratory is a joint series with LCGC and Spectroscopy, profiling analytical scientists and their research groups at universities all over the world. This series spotlights the current chromatographic and spectroscopic research their groups are conducting, and the importance of their research in analytical chemistry and specific industries. In this “Inside the Laboratory –– Women in Separation Science” special edition PDF, we profile four industry leaders and the impact that their research is having in specific fields such as environmental analysis, forensics, national security, and drug development.