CESI-MS: A New Perspective for Metabolic Profiling of Body Fluids

August 22, 2011

The Column

The Column, The Column-08-22-2011, Volume 7, Issue 15

Until recently, a promising solution to couple capillary electrophoresis to electrospray ionization mass spectrometry has only been available to a small group of experts.

Until recently, a promising solution to couple capillary electrophoresis to electrospray ionization mass spectrometry has only been available to a small group of experts. Now, a novel front-end separation and ionization technology, developed by Beckman Coulter, is opening up the technique to a wider audience. This has the potential to offer highly sensitive analysis, providing scientists with important, previously unavailable information — for example, the detection of low-abundance metabolites in body fluids and enabling more extended coverage of the metabolome.

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