LCGC Europe?s digital publication, The Column and LCGC North America?s digital publication, The Peak are to join forces to reach a global audience in July.
LCGC Europe’s digital publication, The Column and LCGC North America’s digital publication, The Peak are to join forces to reach a global audience in July. With a combined circulation of 139,000 readers throughout Europe, North America, Asia and the Middle East, the new publication will take on the name of the successful European version, The Column and continue to be delivered twice monthly to subscribers’ inboxes with a screen-optimized format designed to improve readability. Archived editions will also be available on the website www.chromatographyonline.com
Content will include:
Features: Application-based articles incorporating the latest scientific advances providing practical use to the reader.
News: All the latest news surrounding company acquisitions, current research, conferences and other exciting developments within the industry.
Incognito: A sometimes controversial viewpoint on developments, trends and factors affecting those working within the separation science industry.
Market Trends and Analysis: Current facts and statistics on techniques and trends within the separation science industry.
Tips and Tricks: GPC/SEC: Practical advice on how to maximize the benefits of this versatile technique.
Q&A: Interviews with key personnel from both academia and industry explaining recent research and developments in technology.
Events and Training: An up-to-date listing of key dates in the global chromatography calendar.
Products: A selection of the latest chromatographic equipment dedicated to specific techniques.
Coming up in the next issue…
• Trends in sample preparation for phytochemical determination
• Global concerns drive LC development
• Q&A: Terrell Mathews on core-shell technology
• Latest events and training opportunities
LC–MS/MS Quantification of Plasma Proteins in Elephant Seals to Advance Wildlife Conservation
November 12th 2024Liquid chromatography and tandem mass spectrometry (LC–MS/MS) was used to show that repeated stress can cause delayed but sustained changes in blood plasma proteins associated with water conservation, immune responses, fat metabolism, insulin sensitivity, iron recycling, and hormone transport in elephant seals. Some of these changes may be novel markers of recent and chronic stress exposure in marine mammals.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.