Editorial Director
Laura Bush
LBush@mjhlifesciences.com
LCGC North America
Managing Editor
John Chasse
JChasse@mjhlifesciences.com
Senior Technical Editor
Jerome Workman
JWorkman@mjhlifesciences.com
Associate Editor
Cindy Delonas
CDelonas@mjhlifesciences.com
Assistant Editor
Will Wetzel
WWetzel@mjhlifesciences.com
LCGC Europe, LCGC Asia Pacific, The Column
Editor-in-Chief
Alasdair Matheson
amatheson@mjhlifesciences.com
Temporary Managing Editor
Lily Atkins
LAtkins@mjhlifesciences.com
Managing Editor
Kate Jones
kjones@mjhlifesciences.com
Associate Editor
Lewis Botcherby
lbotcherby@mjhlifesciences.com
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
Using Chromatography to Explore Fluorescent Bioactive Compounds in the Coelomic Fluid of Earthworms
February 6th 2025A study aiming to identify fluorescent bioactive compounds in the coelomic fluid of earthworms, as well as to investigate their structural and functional characteristics for possible use in biomedical applications, utilized a variety of chromatographic techniques.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.