We discuss polyolefins and high temperature GPC in terms of engineering advances.
The first GPC instrument incorporated a pump, an injection valve, a column oven and a RI detector. Quite some engineering ingenuity was required in those days to have a constant flow pump that was particularly required in GPC, where a small change in flow could cause large molar mass errors, and to have a stable RI detector at high temperature (with RI being known to have strong temperature dependency). It is interesting to notice that the very first GPC was targeted at high temperature applications. This certainly showed the importance that the knowledge of the molar mass distribution of polyolefins had in the design of new resins. This leads us on to discuss polyolefins and high temperature GPC in terms of engineering advances.
Quantifying Isavuconazole in Dried Blood Spots Using HPLC
May 21st 2025Isavuconazole, an antimycotic agent used to treat fungal infections, can typically be found during dried blood spot sampling. However, there are obstacles that keep it from being an ideal approach for properly determining the drug’s presence.
HPLC 2025 Preview: On The Road With Your Chromatograph?
Published: May 21st 2025 | Updated: May 21st 2025Brett Paull from the University of Tasmania, Tasmania and his team describe the latest development in portable LC instruments and their experience of taking portable systems out to the field.
HPLC 2025 Preview: The Road To Sustainable Analytical Chemistry
May 20th 2025Elia Psillakis from the Technical University of Crete, Greece, and winner of this year’s Silver Jubilee Award from the Chromatographic Society, which will be presented at HPLC 2025, gives an update on current initiatives in green analytical chemistry.