In Part 2 of "Conversations with Michael Dong," the LCGC column editor discusses HPLC columns for pharmaceutical analysis and the case for short columns.
News|Articles|October 23, 2025
Executive Summary: Supporting mRNA Development With Quantitative Expression Analysis
Quantitative protein expression analysis is essential for advancing mRNA therapeutics, providing the data needed to confirm effective and targeted protein production. This article explores key assay development strategies, analytical challenges, and the application of advanced liquid chromatography-mass spectrometry (LC-MS) techniques to achieve precise and reproducible quantitation of proteins expressed from mRNA therapies.
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