News|Articles|October 23, 2025
Executive Summary: Supporting mRNA Development With Quantitative Expression Analysis
Key Takeaways
Quantitative protein expression analysis is essential for advancing mRNA therapeutics, providing the data needed to confirm effective and targeted protein production. This article explores key assay development strategies, analytical challenges, and the application of advanced liquid chromatography-mass spectrometry (LC-MS) techniques to achieve precise and reproducible quantitation of proteins expressed from mRNA therapies.
Newsletter
Join the global community of analytical scientists who trust LCGC for insights on the latest techniques, trends, and expert solutions in chromatography.
Related Content
Trending on LCGC International
1
Native Capillary Electrophoresis–Mass Spectrometry Enables Quantitative Profiling of Endogenous Protein Complexes
2
Event Preview: 2nd Green Analytical Chemistry Workshop
3
Validated LC–MS/MS Method for Therapeutic Drug Monitoring of Thiopurine Metabolites in Red Blood Cells
4
Best of the Week: Voices From the Analytical Front Line
5