Fast LC Method Development of Spice Cannabinoids Using MaxPeak™ Premier Columns and a Systematic Screening Approach Fast LC Method

The use of method development software with analytical quality by design (AQbD) approaches can produce robust methods but are limited by both access to the software and user proficiency. Other approaches require more manual intervention to select the correct conditions, interpret the results, and make decisions based on the data. This application note, we explore using a systematic screening protocol to develop a method for the analysis of a mixture of nine structurally similar spice cannabinoids.