Waters | Authors


Quick and Robust Sample Preparation for Tryptic Peptide Mapping

In this work we discuss an automatable sample preparation protocol for peptide mapping used in QC, bioprocess, analytical development, and research environments to deliver comprehensive information about the primary structure of biotherapeutic proteins.

Versatile and Rapid Digestion Protocols for Biopharmaceutical Characterization

In this work we discuss how to achieve complete and clean trypsin digestion with an enzyme that provides a balance of missed cleavage, non-specific cleavage, and trypsin autolysis.

Automated High-Throughput LC-MS Focused Peptide Mapping of Monoclonal Antibodies in Microbioreactor Samples

In this work we discuss an automated high-throughput sample preparation method and fast LC-MS peptide mapping for Critical Quality Attribute (CQA) peptide measurement that was developed for low volume and low concentration microbioreactor samples.

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Increase Lab Productivity Anytime, From Anywhere

The waters_connect™ System Monitoring is the latest innovation in lab management, providing real-time information for all Empower-controlled chromatography systems via the waters_connect cloud platform. Coordinating laboratory work and responding dynamically to changing priorities has never been easier.

Quick, Clean, and Complete Peptide Mapping for mAbs (Apr 2023)

Complete and clean trypsin digestion can be achieved with an enzyme that provides a balance of low levels of missed cleavage, non-specific cleavage, and trypsin autolysis. RapiZyme, a next generation trypsin, offers efficiency and reproducibility.