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Articles

High-Speed Sensitive Analysis of Sunitinib and Related Metabolites Through UPLC-MS/MS

Tyrosine Kinase Inhibitors (TKIs) are a class of small molecule drugs used to alter cell growth pathways for the treatment of cancer. Specifically, Sunitinib, a TKI on the market, is available to treat a variety of cancers including pancreatic cancer. Here we create a method to support the therapeutic drug monitoring of Sunitinib and its active metabolite.

What Challenges do High-Performance Surface Consumables Solve?

How standardized, high-performance surface consumables solve the challenge of non-specific adsorption for metal-sensitive analytes in bioseparations.

Improved Separation Performance of mAbs and ADCs

This application note discusses SEC and how to reduce undesired secondary interactions between proteins and the LC column hardware.