The Monday afternoon session on “Food Safety & Chemistry: Foodomics, Allergens, Bacteria, Foods, and Supplements,” will be held 2:30-4:30 pm in Room B405-407. The session, chaired by Michelle Colgrave, Molecular Analysis Team Leader in CSIRO Agriculture and Food, based at the Queensland Bioscience Precinct in Brisbane, Australia, addresses topics related to the analysis of coffee, milk, carbohydrates, quinoa, wine, and more.
The Monday afternoon session on “Food Safety & Chemistry: Foodomics, Allergens, Bacteria, Foods, and Supplements,” will be held 2:30-4:30 pm in Room B405-407. The session, chaired by Michelle Colgrave, Molecular Analysis Team Leader in CSIRO Agriculture and Food, based at the Queensland Bioscience Precinct in Brisbane, Australia, addresses topics related to the analysis of coffee, milk, carbohydrates, quinoa, wine, and more.
The talks are as follows:
2:30 pm: “Towards a Proper Drop Time for Coffee Beans during Roasting with Maximized Antioxidant Capacity Using Photoionization Mass Spectrometry,” presented by Jan Heide of the University of Rostock, in Rostock, Germany.
2:50 pm: “PRM-based MS Method for Detection of Milk-Derived Ingredients from a Processed Food Matrix,” presented by Bini Ramachandran of the Food Allergen Research and Resource Program at the University of Nebraska, in Lincoln, Nebraska.
3:10 pm: “Development of an Encyclopedia of Food Carbohydrates: A Rapid-Throughput LC-MS Based Approach to Global Carbohydrate Analysis of 1000 Foods,” presented by Matthew Amicucci of the University of California, in Davis, California.
3:30 pm: “Novel Dereplication Strategy for Comprehensive Studying the Unique Composition of Saponins in Taiwan Quinoa Using High-Resolution Mass Spectrometry,” presented by Hong-jhang Chen of the National Taiwan University, in Taipei, Taiwan.
3:50 pm: “A Novel, Step-Wise Nutrimetabolomics Approach Reveals Small Molecule-Associated Changes in a DASH-Diet Study,” presented by Nichole Reisdorph of the University of Colorado Anschutz Medical Campus, in Aurora, Colorado.
4:10 pm: “Fast Profiling and Classification of Wines and Wine Quality via SAWN-MS,” presented by Garry Corthals of the University of Amsterdam, in Amsterdam, Netherlands.
LC–MS/MS Quantification of Plasma Proteins in Elephant Seals to Advance Wildlife Conservation
November 12th 2024Liquid chromatography and tandem mass spectrometry (LC–MS/MS) was used to show that repeated stress can cause delayed but sustained changes in blood plasma proteins associated with water conservation, immune responses, fat metabolism, insulin sensitivity, iron recycling, and hormone transport in elephant seals. Some of these changes may be novel markers of recent and chronic stress exposure in marine mammals.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Exploring The Chemical Subspace of RPLC: A Data-driven Approach
November 11th 2024Saer Samanipour from the Van ‘t Hoff Institute for Molecular Sciences (HIMS) at the University of Amsterdam spoke to LCGC International about the benefits of a data-driven reversed-phase liquid chromatography (RPLC) approach his team developed.