Alasdair Matheson | Authors

Articles

Looking into Lipids

Lipidomics is one of the youngest branches of “omics” research. Maria Fedorova from Leipzig University, in Leipzig, Germany, discusses the latest trends and challenges in lipidomics research and highlights how innovative bioinformatics solutions are addressing data handling issues in this evolving field.

The Benefits of Data-Independent Acquisition in Metabolomics

Data-independent acquisition (DIA) makes it possible to re-interrogate data from earlier analyses to determine if new compounds have appeared in a sample previously analyzed. In this interview, Craig Wheelock of the Karolinska Institute discusses the use of DIA in metabolomics.

Going Green in Pharmaceutical Analysis

LCGC Europe spoke to Yong Liu and Adam Socia from MSD about the cost-saving benefits of implementing green chromatography in the pharmaceutical sector, the importance of analytical method volume intensity (AMVI), and effective practices to reduce solvent consumption and replace harmful solvents, including supercritical fluid chromatography (SFC), fast chromatography, and “cocktail chromatography”.

Going Green in Pharmaceutical Analysis

LCGC Asia Pacific spoke to Yong Liu and Adam Socia from MSD about the cost-saving benefits of implementing green chromatography in the pharmaceutical sector, the importance of analytical method volume intensity (AMVI), and effective practices to reduce solvent consumption and replace harmful solvents, including supercritical fluid chromatography (SFC), fast chromatography, and “cocktail chromatography”.

Entering the Second Dimension

LCGC Europe spoke to Alina Muscalu from the Organic Contaminants Section at Ontario Ministry of the Environment, Conservation and Parks (MECP) in Toronto, Canada, about the practical advances in environmental analysis using comprehensive GC×GC for targeted and nontargeted analysis, the role of GC×GC in routine analysis, and the benefits of using a micro-electron capture detector (μECD) for environmental analysis.

Moving Gas Chromatography Forward

Is gas chromatography a mature technology? LCGC Europe spoke to Ronda Gras about a range of GC projects she has been working on to extend the scope of the technique, including a multi-hyphenated approach combining three modes of detection, a miniaturized micromachined GC system, and a novel in situ method to detect carbon dioxide in various matrices by incorporating 3D-printing technology in a FID.