High-performance liquid chromatography-tandem mass spectroscopy (HPLC–MS/MS) chromatography reveals pyrrolizidine alkaloids (PA)/pyrrolizidine alkaloid N-oxides (PANO) toxin risks in 63 tea samples.
News|Webcasts|June 3, 2024
HPLC Column Troubleshooting – Can We Fix It?
Author(s)YMC Europe GmbH
Webinar Date/Time: Wednesday June 26th 8am PST | 11am EST | 4pm BST | 5pm CET
This webcast will provide useful practical advice on troubleshooting issues relating to HPLC columns and how to minimize and resolve these.
Register Free:
This webcast will provide useful, practical advice on troubleshooting issues relating to HPLC columns and how to minimize and resolve these.
Topics Covered:
- Columns and fittings
- Silica-based column packing, limitations, and batch robustness
- Measuring column performance – resolution, asymmetry, and efficiency
- Overview of ultra-high performance liquid chromatography – advantages and disadvantages
- Common column problems
- High pressure
- Voids
- Reversing columns
- Peak shape issues – what causes tailing and fronting
- Strategies for minimizing column damage caused by sample matrix
- Cleaning and regeneration
Speaker:
Colin Towers
Senior Technical Support Chemist
Element
Colin Towers is a senior technical support chemist with Element based in Glasgow, Scotland. After completing a degree in pharmacy, Towers pursued a career in analytical chemistry. Following 3 years performing routine testing and 3 years conducting instrument maintenance and calibration, he moved into a role as a method development and validation specialist in contract research. He gained 11 years of experience in developing methods for HPLC, LC-MS, GC, GC-MS, and SPE in a high-throughput commercial environment. In addition, he spent 3 years lecturing in forensic analytical toxicology and a further 3 years working as a community pharmacist. Towers has been with Element since 2011 as a technical specialist, consultant, and trainer.
Register Free:
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