HPLC Column Troubleshooting – Can We Fix It?

This webcast will provide useful practical advice on troubleshooting issues relating to HPLC columns and how to minimize and resolve these.

Register Free:
https://www.chromatographyonline.com/ca_w/hplc
Event Overview:

This webcast will provide useful, practical advice on troubleshooting issues relating to HPLC columns and how to minimize and resolve these.

Topics Covered: 

• Columns and fittings
• Silica-based column packing, limitations, and batch robustness
• Measuring column performance – resolution, asymmetry, and efficiency
• Overview of ultra-high performance liquid chromatography – advantages and disadvantages
• Common column problems
• High pressure
• Voids
• Reversing columns
• Peak shape issues – what causes tailing and fronting
• Strategies for minimizing column damage caused by sample matrix
• Cleaning and regeneration

Speaker:

Colin Towers
Senior Technical Support Chemist
Element

Colin Towers is a senior technical support chemist with Element based in Glasgow, Scotland. After completing a degree in pharmacy, Towers pursued a career in analytical chemistry. Following 3 years performing routine testing and 3 years conducting instrument maintenance and calibration, he moved into a role as a method development and validation specialist in contract research. He gained 11 years of experience in developing methods for HPLC, LC-MS, GC, GC-MS, and SPE in a high-throughput commercial environment. In addition, he spent 3 years lecturing in forensic analytical toxicology and a further 3 years working as a community pharmacist. Towers has been with Element since 2011 as a technical specialist, consultant, and trainer.

Register Free:
https://www.chromatographyonline.com/ca_w/hplc