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Pore Size Selection for SEC of Oligonucleotides

Columns of the YMC-Pack Diol SEC series (120–300 Å), which have distinct pore sizes, were tested for their ability to separate DNA of various lengths (10–300mer).

UHPLC/MicroLC High Sensitivity Analysis of Peptides

Demonstration of the sensitivity gain for the Pierce peptide mix, which is achieved when using UHPLC columns of different i.d.s, as well as a micro-LC approach.

Analysis of mRNA Coupled to EGFP (Apr 2023)

mRNA coupled to EGFP (enhanced green fluorescent protein) is analyzed using a widepore YMC-Accura Triart Bio C4 RP column as well as a non-porous BioPro IEX QF column.

SEC Separation of siRNA and its Single Strands

A siRNA duplex and its single strands are separated using different YMC size exclusion columns to identify the most suitable SEC column.

UHPLC-MS of Phospholipids Using Bioinert Columns

Reversed-phase LC–MS analysis of two phospholipids—LPC (16:0) and PC (34:2)—using a bioinert coated column in comparison with a regular stainless steel one.

HILIC Analysis of Oligonucleotides Using Bioinert Columns

Different oligonucleotide mixtures were analyzed using the bioinert coated column YMC-Accura Triart Diol-HILIC in comparison to the conventional stainless steel column.