An Insight into Analytical Quality by Design in the Pharmaceutical Industry

Waters Corporation is merging with BD’s Biosciences and Diagnostic Solutions business in a $17.5 billion deal to expand its capabilities in life sciences and diagnostics.

In episode #37 of Analytically Speaking, podcast host Dr. Jerry Workman speaks with Dr. Austin Daniels, application scientist for Yokogawa Fluid Imaging Technologies, about flow imaging microscopy (FIM), a new technology for sub-visible particle characterization in biologics.

Researchers speculating that exposure to paraben in early childhood is associated with changes in satiety hormones performed analysis of urinary methyl, ethyl, propyl, and butylparaben (MeP, EtP, PrP, BuP) levels in 4–6-year-old children, using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).

This week, LCGC International published a variety of articles on hot topics in separation science. Several analytical techniques were covered in these articles, including gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–MS (LC–MS).

Research conducted by the University of Florida and the University of California used targeted metabolomics in pomegranates to profile essential primary and secondary metabolites, including organic acids, amino acids, sugars, hormones, and phenolic compounds, using gas chromatography mass spectrometry (GC-MS) and liquid chromatography mass spectrometry (LC-MS).