LCGC TV: Liquid Chromatography

August 24, 2015

LCGC TV: Luigi Mondello on the Fundamentals of 2D LC Comprehensive liquid chromatography (LC) is a multidimensional technique that has the potential to increase peak capacity resolution when separating complex mixtures, especially in food analysis.

 LCGC TV: Attila Felinger on Fast Liquid Chromatography

In this new video from LCGC TV, Attila Felinger from the University of Pécs, Hungary, defines the term “fast LC” and discusses how developments in fast LC technology have changed the field of bioanalysis. Watch Here >>

 

LCGC 

TV: Luigi Mondello on the Fundamentals of 2D LC

 Comprehensive liquid chromatography (LC) is a multidimensional technique that has the potential to increase peak capacity resolution when separating complex mixtures, especially in food analysis. In this new video from LCGC TV, Luigi Mondello from the University of Messina, Italy, describes the fundamental principles of 2D LC, and explains the advantages over 1D LC. Watch Here>>

 

LCGC TV: Attila Felinger on Fast Liquid Chromatography

In this new video from LCGC TV, Attila Felinger from the University of Pécs, Hungary, defines the term “fast LC” and discusses how developments in fast LC technology have changed the field of bioanalysis. Watch Here >>

 

LCGC TV: New Carbon-Based Phases for 2D LC

In this new video clip from LCGC TV, Dwight Stoll of Gustavus Adolphus College discusses the development of new carbon-based phases for 2D LC that are well characterized and understood. Watch Here >>

 

 

LCGC TV: The Future Use of 2D LC in Pharmaceutical Analysis

Two-dimensional liquid chromatography has moved from academia into industry. In this new video from LCGC TV, Kelly Zhang from Genentech discusses the next steps needed for the use of 2D LC by the pharmaceutical industry. Watch Here >>

 

LCGC TV: How to Get More Out of Modern HPLC Systems

Do you want to get more out of modern high performance liquid chromatography (HPLC) systems? In this new video from LCGC TV, Richard Henry, a consultant from State College (Pennsylvania, USA), discusses what chromatographers need to learn, from measuring dispersion and using Van Deemter and Van ‘t Hoff plots to getting familiar with mobile phase variables. Watch Here >>

 

LCG

TV: Frederic Lynen on Performing UHPLC in Bioanalysis 

Are mass spectrometers becoming too sensitive? Does performing ultrahigh-performance liquid chromatography (UHPLC) increase matrix effects? In this new video clip from LCGC TV, Frederic Lynen of Ghent University in Belgium discusses the challenges faced by analysts working in the field of bioanalysis and comments on potential solutions. Watch Here >>

   

LCGC TV: 2D LC Methods for Analyzing Pharmaceutical Impurities
Two-dimensional liquid chromatography has moved from academia into industry. In this new video, Kelly Zhang of Genentech talks about the advantages gained by developing a two-dimensional LC method for analyzing impurities in pharmaceuticals, and gives practical examples. Watch Here>>

 

 

 LCGC TV: Is 2D LC Ready for Prime Time Analysis?

2D LC has huge potential to increase the resolving power of separations involving complex samples. In this new video clip, Dwight Stoll of Gustavus Adolphus College considers if this technique is ready to be adopted by chromatographers working in industry. Watch Here>>

 

LCGC TV: Mary Ellen McNally on Maintaining Precision During Method Transfer 

  Transferring methods between laboratories can be extremely difficult. In this new short video from

LCGC

TV, Mary Ellen McNally from DuPont Crop Protection gives her advice on best practices for maintaining precision during method transfer. 

Watch Here>>

       

LCGC TV: Richard Henry on Optimizing UHPLC Methods

Ultrahigh-performance liquid chromatography (UHPLC) offers improved run-times and enhanced resolution when compared with conventional liquid chromatography (LC) methods. In this new video from LCGC TV, Richard Henry, a consultant from State College (Pennsylvania, USA), gives his advice on how to select UHPLC column size and discusses the features of an optimal UHPLC instrument.

 

LCGC TV: Dierdre Cabooter on Method Development in UHPLC 

The Kinetic Plot method is a useful tool in LC method development to compare the performance of different LC columns with each other. In this new video from LCGC TV, Deirdre Cabooter from KU Leuven (Belgium) describes the range of techniques that it can be applied to and how it can help analysts in practice. Watch Here>>

 

LCGC TV: Richard Henry on Narrow Particle Size Distribution in HPLC Columns

Fully porous particle columns with narrow particle distribution can improve the efficiency of HPLC separations. In this new video from LCGC TV, Richard Henry, a consultant from State College (Pennsylvania, USA) discusses the advantages of narrow particle distribution and whether optimized LC instruments are required for optimum performance. Watch Here>>

 

LCGC TV: Using the Variable Length Method Development Strategy to Develop Successful UHPLC Methods

The Kinetic Plot method is a useful tool in LC method development to compare the performance of different LC columns with each other. In this new video from LCGC TV, Deirdre Cabooter from KU Leuven (Belgium) describes how to use the variable length method development strategy to develop successful UHPLC methods and how this approach can save time for the analyst. Watch Here>>

 

LCGC TV: Mary Ellen McNally on Analytical Precision 
In these two new videos from LCGC TV, Mary Ellen McNally from DuPont Crop Protection addresses the issue of precision, covering the reasons why the precision of a measurement is so important and the factors that can influence the precision of an active ingredient assay.

 

 

LCGC TV: Why You Need to Listen . . . Even to Your Instrument

We all have always been told that we need to listen, and to listen more carefully. Growing up, we were told to listen to our parents and our teachers. As adults, we need to listen more attentively to our spouses at home and our bosses, colleagues, and customers at work. But have you considered listening to your analytical instruments? Here is why you should. Watch Here>>

 

LCGC TV: Is Two-Dimensional LC Worth the Effort?

Two-dimensional liquid chromatography (2D LC) is a powerful technique, but method development is more involved and time-consuming. So for what types of analyses does it make sense to invest the extra effort to develop a 2D LC method instead of a 1D method? Dwight Stoll explains. Watch Here>>

 

LCGC TV: Common Errors in the Laboratory

We all make mistakes. The first step to correcting them is recognizing them, and learning the right way to do things. In two new short videos, Merlin Bicking talks about two common errors that chromatographers make, and how to avoid them. Watch Here>>

 

LCGC TV: The Future of Monoliths and Chips

Monoliths have received renewed attention in the past few years. Will they - or chip-based columns - ever compete with particle-based columns? In a short video interview, Dick Henry weighs in. Watch Here>>

 

 

LCGC TV: Deirdre Cabooter on Method Development in UHPLC

Performing ultrahigh-performance liquid chromatography (UHPLC) can significantly reduce analysis time without compromising on efficiency by using sub 2-μm particles that allow increased velocity while maintaining selectivity. In this new short interview, Deirdre Cabooter of KU Leuven in Belgium, discusses the advantages of using UHPLC in method development and tips to follow when transferring methods from UHPLC to HPLC instrumentation. Watch here>>

 

LCGC TV: Two-Dimensional LC in Pharmaceutical Analysis: Advantages and Challenges

Two-dimensional liquid chromatography has moved from academia into industry. In two new short video interviews, Kelly Zhang of Genentech talks about the advantages gained by developing a two-dimensional LC method for analyzing impurities in pharmaceuticals, as well as the challenges in developing the method. Watch Here>>

 

LCGC TV: Richard Henry on Fully Porous vs. Superficially Porous Particles

Superficially porous particles for HPLC columns – often called "core–shell" particles have gotten a lot of attention in recent years because of their excellent performance. Yet so far, columns made with fully porous particles are still the most widely used. Will superficially porous particles eventually take over? Watch here>>

 

LCGC TV: Dwight Stoll on 2D LC

In this new video interview, Dwight Stoll of Gustavus Adolphus provides advice about key decisions in method development, common errors to avoid, and other advice for getting started with 2D LC. Watch here>>

     

LCGC TV: Richard Henry on "Do We Need More LC Phases?

Dick Henry, consultant, discusses a trend that could renew efforts towards developing novel LC stationary phases with improved selectivity, peak symmetry, and stability. The question is, however, whether we really need more stationary phases in HPLC. Watch the video and find out. Watch here>>

 

LCGC TV: Mary Ellen McNally on Common Error with Internal Standard Methods

Internal standards are an important tool of analytical chemists, yet errors in their usage are common. Mary Ellen McNally of DuPont Crop Protection offers advice for how to introduce an internal standard and how to avoid common errors with internal standard methods. Watch here>>

 

LCGC TV: Joe Foley on Sequential Elution Liquid Chromatography

Sequential-elution LC is a new methodology for the analysis of complex samples. In a new video initiative from LCGC, Joe Foley, Professor of Chemistry at Drexel University, Philadelphia, Pennsylvania, USA, explains very briefly how it works and its advantages over conducting multiple runs of conventional LC. Watch Here>>